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Determined by the final results with the pre- and postnatal study, the developmental NOAEL check my site is a lot less than one mg/kg/working day. Dependant on check my reference plasma exposures within the rat developmental toxicity study, 1 mg/kg/working day in the pregnant rat is approximated to generate complete AUC values for unbound vardenafil and its important metabolite corresponding to the human AUC with the MRHD of 20 mg.
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